A kidney-targeted chitosan-melanin nanoplatform for alleviating diabetic nephropathy through modulation of blood glucose and oxidative stress

Diabetic nephropathy (DN) is a serious complication in patients with diabetes, whose expansion process is closely related to oxidative stress caused by hyperglycemia. Herein, we report a chitosan-targeted dagliflozin-loaded melanin nanoparticle (CSMDNPs) that can selectively accumulate in injured ki...

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Veröffentlicht in:	International journal of biological macromolecules 2024-04, Vol.264 (Pt 2), p.130663-130663, Article 130663
Hauptverfasser:	Sun, Jinghua, Han, Juanjuan, Dong, Jie, Zhai, Xiaoyan, Zhang, Ruiping
Format:	Artikel
Sprache:	eng
Schlagworte:	Dapagliflozin Diabetic nephropathy Kidney-targeted therapy Melanin nanoparticles Photoacoustic imaging
Online-Zugang:	Volltext
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