Non-viral delivery of RNA for therapeutic T cell engineering

[Display omitted] Adoptive T cell transfer has shown great success in treating blood cancers, resulting in a growing number of FDA-approved therapies using chimeric antigen receptor (CAR)-engineered T cells. However, the effectiveness of this treatment for solid tumors is still not satisfactory, emp...

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Veröffentlicht in:	Advanced drug delivery reviews 2024-05, Vol.208, p.115215, Article 115215
Hauptverfasser:	Berdecka, Dominika, De Smedt, Stefaan C., De Vos, Winnok H., Braeckmans, Kevin
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer immunotherapy Cell engineering Cell Engineering - methods Cell therapy Gene therapy Humans Immunotherapy, Adoptive - methods Neoplasms - pathology Non-viral delivery RNA - metabolism RNA therapeutics T cell T-Lymphocytes
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