Human lead exposure in a late 19th century mental asylum population

Lead isotope ratios and lead (Pb) levels were analyzed in 33 individuals from a forgotten cemetery at the Colorado Mental Health Institute at Pueblo, Colorado dating to 1879–1899. Isotopic ratios from healing bone fractures, cortical bone, and tooth dentine provide information about sources of Pb ex...

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Veröffentlicht in:The Science of the total environment 2007, Vol.372 (2), p.463-473
Hauptverfasser: Bower, Nathan W., McCants, Sarah A., Custodio, Joseph M., Ketterer, Michael E., Getty, Stephen R., Hoffman, J. Michael
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container_end_page 473
container_issue 2
container_start_page 463
container_title The Science of the total environment
container_volume 372
creator Bower, Nathan W.
McCants, Sarah A.
Custodio, Joseph M.
Ketterer, Michael E.
Getty, Stephen R.
Hoffman, J. Michael
description Lead isotope ratios and lead (Pb) levels were analyzed in 33 individuals from a forgotten cemetery at the Colorado Mental Health Institute at Pueblo, Colorado dating to 1879–1899. Isotopic ratios from healing bone fractures, cortical bone, and tooth dentine provide information about sources of Pb exposures over a range of time that illuminates individual's life histories and migration patterns. Historical records and Pb production data from the 19th century were used to create a database for interpreting Pb exposures for these African, Hispanic and European Americans. The analysis of these individuals suggests that Pb exposure noticeably impacted the mental health of 5–10% of the asylum patients in this frontier population, a high number by standards today, and that differences exist in the three ancestral groups' exposure histories.
doi_str_mv 10.1016/j.scitotenv.2006.10.019
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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Adult and adolescent clinical studies
Archaeology
Biological and medical sciences
Bone
Bone and Bones - chemistry
Chemical and industrial products toxicology. Toxic occupational diseases
Colorado
Diagenesis
Environmental Exposure - history
History, 19th Century
Hospitals, Psychiatric
Humans
ICP-OES
Isotope
Lead - analysis
Lead Poisoning - epidemiology
MC-ICP-MS
Medical sciences
Mental Disorders - chemically induced
Metals and various inorganic compounds
Mortuary Practice
Organic mental disorders. Neuropsychology
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
TIMS
Tooth - chemistry
Toxicology
title Human lead exposure in a late 19th century mental asylum population
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