Recombinant Human Thrombopoietin Promotes Platelet Engraftment in Severe Aplastic Anemia Patients Following Treatment With Haploid Hematopoietic Stem Cell Transplantation using Modified Post-Transplantation Cyclophosphamide

•rhTPO promoted platelet recovery after Haplo-HSCT in SAA patients received PTCy.•rhTPO did not significantly impact transplant-related complications or survival.•rhTPO demonstrated good safety profiles without evident adverse reactions. Recombinant human TPO (rhTPO) promotes platelet engraftment in...

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Veröffentlicht in:	Transplantation and cellular therapy 2024-05, Vol.30 (5), p.500-509
Hauptverfasser:	Fu, Andie, Peng, Yizhou, Cheng, Ping, Wu, Jiaying, Zhu, Xiaojian, Yang, Yang, Huang, Lifang, Wang, Na, Wang, Jue, Xu, Jinhuan, Wan, Yuling, Cao, Yang, Wei, Jia, Xiao, Yi, Meng, Fankai, Cheng, Hui, Zhang, Yicheng, Zhang, Donghua
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anemia, Aplastic - therapy Blood Platelets - drug effects Child Cyclophosphamide - therapeutic use Female Graft vs Host Disease Haploid hematopoietic stem cell transplantation Hematopoietic Stem Cell Transplantation - methods Humans Male Middle Aged Platelet engraftment Platelet Transfusion Post-transplantation cyclophosphamide Recombinant human thrombopoietin Recombinant Proteins - administration & dosage Recombinant Proteins - therapeutic use Severe aplastic anemia Thrombopoietin - administration & dosage Thrombopoietin - therapeutic use Transplantation, Haploidentical Young Adult
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