Fenugreek extract improves diabetes-induced endothelial dysfunction via the arginase 1 pathway

Endothelial dysfunction (ED) is an initiating trigger and key factor in vascular complications, leading to disability and mortality in individuals with diabetes. The research concerning therapeutic interventions for ED has gained considerable interest. Fenugreek, a commonly used edible plant in diet...

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Veröffentlicht in:	Food & function 2024-04, Vol.15 (7), p.3446-3462
Hauptverfasser:	Qiu, Dingbang, Hu, Jinxin, Zhang, Shaoying, Cai, Wanjun, Miao, Jingwei, Li, Pengdong, Jiang, Wenyue
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arginase Chemical composition Chromatography Diabetes Diabetes mellitus Diabetes Mellitus, Experimental - drug therapy Diabetes Mellitus, Experimental - metabolism Endothelial Cells Ethanol Exosomes Fenugreek Flavonoids Glucose Glucose - metabolism Immunohistochemistry Kinases Liquid chromatography MAP kinase Mass spectrometry Mass spectroscopy Mice Nitric oxide Nitric Oxide Synthase Type III - metabolism Nitric-oxide synthase p38 Mitogen-Activated Protein Kinases - metabolism Phospholipids Plant Extracts Protein expression Proteins Quadrupoles Rats Saponins Serum Streptozocin Therapeutic applications Trigonella Trigonella foenum-graecum
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