Individual polysaccharide quantification in polyvalent pneumococcal conjugate vaccine using rate nephelometry

The multivalent pneumococcal conjugate vaccine (PCV) contains purified polysaccharides of different serotypes conjugated to a carrier protein. Testing the final formulated product for individual serotype polysaccharide content is critical in vaccine quality control which requires an assay specific t...

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Veröffentlicht in:	Journal of immunological methods 2023-10, Vol.521, p.113539-113539, Article 113539
Hauptverfasser:	Rajendar, Burki, Pydigummala, Jaya Sheela, Rao, Ganti Sreenivasa, Chigurambotla, Ramakrishna, Matur, Ramesh V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Activated quenched polysaccharide digestion epitopes Haemophilus Individual serotype polysaccharide quantification influenza nephelometry Pneumococcal conjugate vaccine polysaccharides quality control Rate nephelometry reference standards Salmonella serotypes shelf life Streptococcus pneumoniae trypsin vaccines
Online-Zugang:	Volltext
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