Proximity ligation initiated DNAzyme-powered catalytic hairpin assembly for sensitive and accurate microRNA analysis

MicroRNAs (miRNAs) play a significant role in regulating diverse physiological processes, and are regarded as novel diagnostic biomarkers. However, the sensitive and reliable miRNA detection remains a huge challenge. Herein, we propose a proximity ligated initiated magnesium ion (Mg2+)-dependent DNA...

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Veröffentlicht in:	Analytical biochemistry 2023-11, Vol.680, p.115299-115299, Article 115299
Hauptverfasser:	Su, Jiaguang, Zheng, Wenjun, Pan, Yanbin
Format:	Artikel
Sprache:	eng
Schlagworte:	biomarkers Catalytic hairpin reaction (CHA) detection limit DNAzyme magnesium microRNA MicroRNAs (miRNAs) Proximity ligation rapid methods
Online-Zugang:	Volltext
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