Analysis of cholesterol-recognition motifs of the plasma membrane Ca2+-ATPase

The plasma membrane Ca 2+ -ATPase (PMCA) is crucial for the fine tuning of intracellular calcium levels in eukaryotic cells. In this study, we show the presence of CARC sequences in all human and rat PMCA isoforms and we performed further analysis by molecular dynamics simulations. This analysis foc...

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Veröffentlicht in:	Journal of bioenergetics and biomembranes 2024-06, Vol.56 (3), p.205-219
Hauptverfasser:	Delgado-Coello, Blanca, Luna-Reyes, Ismael, Méndez-Acevedo, Kevin M., Bravo-Martínez, Jorge, Montalvan-Sorrosa, Danai, Mas-Oliva, Jaime
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Anatomy Animal Biochemistry Biochemistry Bioorganic Chemistry Ca2+-transporting ATPase Calcium Calcium (intracellular) Calcium homeostasis Calcium ions Chemistry Chemistry and Materials Science Cholesterol Conformation Energy value Histology Homeostasis Intracellular Isoforms Lipids Membranes Molecular dynamics Morphology Organic Chemistry Phospholipids Simulation Transmembrane domains
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