STRN3 promotes tumour growth in hepatocellular carcinoma by inhibiting the hippo pathway

HCC is a globally high‐incidence malignant tumour, and its pathogenesis is still unclear. Recently, STRN3 has been found to be elevated in various tumours, but its expression and biological functions in HCC have not been studied. In the study, clinical correlation analysis was performed on 371 liver...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2024-03, Vol.28 (6), p.e18147-n/a
Hauptverfasser:	Zhu, Jie, Tang, Wenjia, Fang, Peiqi, Wang, Chong, Gu, Meixiu, Yang, Wenjing, Pan, Baishen, Wang, Beili, Guo, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Autoantigens Calmodulin-Binding Proteins - metabolism Carcinoma, Hepatocellular - pathology Cell Line, Tumor Cell migration Cell Movement - genetics Cell proliferation Cell Proliferation - genetics Cells Correlation analysis Flow cytometry Gene Expression Regulation, Neoplastic Genes Genomes Genomics Growth factors Hepatocellular carcinoma hippo pathway Hippo Signaling Pathway Humans Immunofluorescence Immunohistochemistry Kinases Liver cancer Liver Neoplasms - pathology Patients Phosphatase Protein Serine-Threonine Kinases - genetics Protein Serine-Threonine Kinases - metabolism Proteins Signal Transduction STRN3 TCGA database Tumors Western blotting Wound healing YAP Yes-associated protein
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