Current advances in targeted therapy for metastatic colorectal cancer – Clinical translation and future directions

•Breakthroughs in targeted therapy for metastatic colorectal cancer stems from advances in translational research.•Tumor genotyping, primary tumor location and ctDNA monitoring contribute to precision oncology.•Pivotal trials of non-cytotoxic regimens targeting BRAF, HER2 and RAS (K12C) alterations...

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Veröffentlicht in:	Cancer treatment reviews 2024-04, Vol.125, p.102700-102700, Article 102700
Hauptverfasser:	Johnson, David, Chee, Cheng Ean, Wong, Wesley, Lam, Rachel C.T., Tan, Iain Bee Huat, Ma, Brigette B.Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Metastatic colorectal cancer Next generation sequencing Targeted therapy
Online-Zugang:	Volltext
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