Current use of antithymoglobulin as induction regimen in kidney transplantation: A review

Currently, various immunosuppressive drugs are used in organ transplantation. In particular, antithymoglobulin is a widely used drug in kidney transplantation in Korea, accounting for 20% of all induction therapy. According to existing studies, antithymoglobulin induction therapy has several advanta...

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Veröffentlicht in:Medicine (Baltimore) 2024-03, Vol.103 (9), p.e37242-e37242
Hauptverfasser: Park, Byung Hwa, Kim, Ye Na, Shin, Ho Sik, Jung, Yeonsoon, Rim, Hark
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Kim, Ye Na
Shin, Ho Sik
Jung, Yeonsoon
Rim, Hark
description Currently, various immunosuppressive drugs are used in organ transplantation. In particular, antithymoglobulin is a widely used drug in kidney transplantation in Korea, accounting for 20% of all induction therapy. According to existing studies, antithymoglobulin induction therapy has several advantages and disadvantages compared with other immunotherapies depending on the kidney transplant situation (dead donor, living donor, low-risk recipient, and high-risk recipient) or antithymoglobulin dose. In this review, we summarize the research conducted so far on antithymoglobulin and hope that antithymoglobulin research on kidney transplantation will be actively conducted in the future.
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subjects Antilymphocyte Serum - therapeutic use
Clinical Protocols
Graft Rejection - prevention & control
Graft Survival
Humans
Immunosuppressive Agents - therapeutic use
Kidney Transplantation
Living Donors
title Current use of antithymoglobulin as induction regimen in kidney transplantation: A review
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