Transporter targeted-carnitine modified pectin-chitosan nanoparticles for inositol hexaphosphate delivery to the colon: An in silico and in vitro approach

Orally targeted delivery systems have attracted ample interest in colorectal cancer management. In this investigation, we developed Inositol hexaphosphate (IHP) loaded Tripolyphosphate (Tr) crosslinked Pectin (Pe) Chitosan (Ch) nanoparticles (IHP@Tr*Pe-Ch-NPs) and modified them with l-Carnitine (CE)...

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Veröffentlicht in:	International journal of biological macromolecules 2024-04, Vol.263 (Pt 2), p.130517-130517, Article 130517
Hauptverfasser:	Mishra, Nidhi, Sharma, Madhu, Mishra, Pooja, Nisha, Raquibun, Singh, Priya, Pal, Ravi Raj, Singh, Neelu, Singh, Samipta, Maurya, Priyanka, Pant, Suyash, Mishra, Prabhat Ranjan, Saraf, Shubhini A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bio-polymeric nanoparticles Carnitine Chitosan Colon Colon targeting Drug Carriers Humans MCF-7 Cells Nanoparticles Pectins - pharmacology Phytic Acid Transporter-targeting
Online-Zugang:	Volltext
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