Lithocholic Acid Alleviates Deoxynivalenol-Induced Inflammation and Oxidative Stress via PPARγ-Mediated Epigenetically Transcriptional Reprogramming in Porcine Intestinal Epithelial Cells

Deoxynivalenol (DON) is a common mycotoxin that induces intestinal inflammation and oxidative damage in humans and animals. Given that lithocholic acid (LCA) has been suggested to inhibit intestinal inflammation, we aimed to investigate the protective effects of LCA on DON-exposed porcine intestinal...

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Veröffentlicht in:Journal of agricultural and food chemistry 2024-03, Vol.72 (10), p.5452-5462
Hauptverfasser: Li, Yanwei, Zhu, Chuyang, Yao, Jiacheng, Zhu, Cuipeng, Li, Zhaojian, Liu, Hao-Yu, Zhu, Miaonan, Li, Kaiqi, Ahmed, Abdelkareem A., Li, Shicheng, Hu, Ping, Cai, Demin
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Sprache:eng
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