Concordance of vacuum compression molding with spray drying in screening of amorphous solid dispersions of itraconazole

[Display omitted] Spray drying is a well-established method for screening spray dried dispersions (SDDs) but is material consuming, and the amorphous solid dispersions (ASDs) formed have low bulk density. Vacuum Compression Molding (VCM) is a potential method to avoid these limitations. This study f...

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Veröffentlicht in:	International journal of pharmaceutics 2024-04, Vol.654, p.123952-123952, Article 123952
Hauptverfasser:	Dhumal, Gaurav, Treffer, Daniel, Polli, James E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amorphous Solid Dispersions Hydroxypropyl methylcellulose acetate succinate Itraconazole Solubility Spray Drying Vacuum Compression Molding
Online-Zugang:	Volltext
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