Regioselective Addition of Sulfur and Amine Nucleophiles To Assemble SC–S, S–N, and Umpolung C–N Bonds: Exploration of the −CBr3 Group as a Synthetic Equivalent of SC–S

The regioselective addition of sulfur and amine nucleophiles to a −CBr3 unit and nitromethyl moiety in a molecule with the installation of a five-diverse bond structure to novel isothiazole-5­(2H)-thione is demonstrated. Umpolung of the nitromethyl group leads to a novel scaffold with selective C–N...

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Veröffentlicht in:	Organic letters 2024-03, Vol.26 (9), p.1874-1879
Hauptverfasser:	Gupta, Ankush, Gururaja, Guddeangadi N.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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