Computational insights on asymmetrical D1 and D2 receptor-mediated chunking: implications for OCD and Schizophrenia

Repetitive thoughts and motor programs including perseveration are bridge symptoms characteristic of obsessive compulsive disorder (OCD), schizophrenia and in the co-morbid overlap of these conditions. The above pathologies are sensitive to altered activation and kinetics of dopamine D 1 and D 2 rec...

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