pXg: Comprehensive Identification of Noncanonical MHC-I–Associated Peptides From De Novo Peptide Sequencing Using RNA-Seq Reads

Discovering noncanonical peptides has been a common application of proteogenomics. Recent studies suggest that certain noncanonical peptides, known as noncanonical major histocompatibility complex-I (MHC-I)-associated peptides (ncMAPs), that bind to MHC-I may make good immunotherapeutic targets. De...

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Veröffentlicht in:	Molecular & cellular proteomics 2024-04, Vol.23 (4), p.100743-100743, Article 100743
Hauptverfasser:	Choi, Seunghyuk, Paek, Eunok
Format:	Artikel
Sprache:	eng
Schlagworte:	bioinformatics immunopeptidomics machine learning noncanonical peptides proteogenomics
Online-Zugang:	Volltext
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