Schisandrin A alleviates renal fibrosis by inhibiting PKCβ and oxidative stress

Renal fibrosis is a common pathway that drives the advancement of numerous kidney maladies towards end-stage kidney disease (ESKD). Suppressing renal fibrosis holds paramount clinical importance in forestalling or retarding the transition of chronic kidney diseases (CKD) to renal failure. Schisandri...

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Veröffentlicht in:	Phytomedicine (Stuttgart) 2024-04, Vol.126, p.155372-155372, Article 155372
Hauptverfasser:	Liu, Hui-Ling, Huang, Zhou, Li, Qing-Zhen, Cao, Yi-Zhi, Wang, Han-Yu, Alolgab, Raphael N., Deng, Xue-Yang, Zhang, Zhi-Hao
Format:	Artikel
Sprache:	eng
Schlagworte:	acute kidney injury Animals blood serum Chronic kidney disease Cyclooctanes Fibrosis histology Kidney Kidney Diseases - drug therapy kidneys Lignans metabolites metabolomics Mice Oxidative Stress PKCβ Polycyclic Compounds renal failure Renal fibrosis renoprotective effect Sch A Transforming Growth Factor beta1 - metabolism Ureteral Obstruction - pathology vimentin
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