Impact of Glycosylation on Protein–Protein Self-Interactions of Monoclonal Antibodies

Protein self-interactions measured via second osmotic virial coefficients (B 22) and dynamic light scattering interaction parameter values (k D) are often used as metrics for assessing the favorability of protein candidates and different formulations during monoclonal antibody (MAb) product developm...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Molecular pharmaceutics 2024-03, Vol.21 (3), p.1414-1423
Hauptverfasser: Palakollu, Veerabhadraiah, Motabar, Lily, Roberts, Christopher J.
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!