Pharmacokinetics, Safety Profile, and Tolerability of Tetramethylpyrazine Nitrone Tablets After Single and Multiple Ascending Doses in Healthy Chinese Volunteers

Background and Objectives Tetramethylpyrazine nitrone (TBN) is a novel tetramethylpyrazine derivative armed with a strong free radical scavenging nitrone moiety. This study aims to evaluate the pharmacokinetics, safety profile, and tolerability of TBN tablets after a single ascending dose (SAD) and...

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Veröffentlicht in:	European journal of drug metabolism and pharmacokinetics 2024-03, Vol.49 (2), p.207-217
Hauptverfasser:	Zhu, Gangzhi, Wang, Liu, Zhong, Shaojin, Han, Shengnan, Peng, Hui, Tong, Mei, He, Xiaoai
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine Human Physiology Medical Biochemistry Original Research Article Pharmaceutical Sciences/Technology Pharmacology/Toxicology Pharmacy
Online-Zugang:	Volltext
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