Clinical management of NUT carcinoma (NC) in Germany: Analysis of survival, therapy response, tumor markers and tumor genome sequencing in 35 adult patients

•Survival is better in absence of primary thoracic manifestations or metastases and with surgery.•Metastases are found most frequently in lymph nodes, bones and soft tissue.•TMB is low, PD-L1 expression is low and mutational signatures of HRD and MSI are absent.•Serum LDH at diagnosis constitutes a...

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Veröffentlicht in:	Lung cancer (Amsterdam, Netherlands) Netherlands), 2024-03, Vol.189, p.107496-107496, Article 107496
Hauptverfasser:	Kloker, Linus D., Sidiras, Mirjana, Flaadt, Tim, Brecht, Ines B., Deinzer, Christoph K.W., Groß, Thorben, Benzler, Katrin, Zender, Lars, Lauer, Ulrich M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biomarkers, Tumor BRD4-NUTM1 Bromodomain Containing Proteins Carcinoma Cell Cycle Proteins Chemotherapy Fusion oncogene Germany Humans Lung Neoplasms Nuclear Proteins - genetics NUT carcinoma Transcription Factors Tumor genome sequencing
Online-Zugang:	Volltext
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