Ferulic acid protects against gamma-radiation induced liver injury via regulating JAK/STAT/Nrf2 pathways

This study aims to evaluate the effect and underlying mechanism of ferulic acid (FA) in alleviating the acute liver injury by ionizing radiation (IR) in vivo. Rats were divided into 4groups (Groups: control, 6Gy irradiated (IRR), FA (50 mg/kg) and FA + IRR). The results showed that FA can effectivel...

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Veröffentlicht in:	Archives of biochemistry and biophysics 2024-03, Vol.753, p.109895, Article 109895
Hauptverfasser:	Gawish, Rania A., Samy, Esraa M., Aziz, Maha M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - metabolism Antioxidants - pharmacology Antioxidants - therapeutic use Chemical and Drug Induced Liver Injury, Chronic Coumaric Acids Ferroptosis Ferulic acid JAK1/STAT3 Liver injury NF-E2-Related Factor 2 - metabolism Nrf2 Rats
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