$Mendelian‐randomization study revealed causal relationship between nonalcoholic fatty liver disease and osteoporosis/fractures$

Mendelian‐randomization study revealed causal relationship between nonalcoholic fatty liver disease and osteoporosis/fractures

Background Patients with nonalcoholic fatty liver disease (NAFLD) are reported to have a higher risk of osteoporosis/fractures; however, the causal relationship remains unclear. Methods Publicly available genome‐wide association studies (GWASs) were used for Mendelian randomization (MR) analysis. GW...

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Veröffentlicht in:	Journal of gastroenterology and hepatology 2024-05, Vol.39 (5), p.847-857
Hauptverfasser:	Pei, Xiong, Jiang, Wei, Li, Lianchi, Zeng, Qingmin, Liu, Chang‐Hai, Wang, Ming, Chen, Enqiang, Zhou, Taoyou, Tang, Hong, Wu, Dongbo
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline phosphatase Beta cells Body Mass Index Bone Density - genetics Bone mineral density Causal inference Consortia Diabetes mellitus Fatty liver Femur Femur Neck - diagnostic imaging Fibrosis Fractures Fractures, Bone - epidemiology Fractures, Bone - etiology Fractures, Bone - genetics Genome-Wide Association Study Genomes Glycated Hemoglobin - metabolism Hemoglobin High density lipoprotein Hip Homeostasis Humans Lipoproteins, HDL - blood Liver diseases Low density lipoprotein Mendelian randomization Mendelian Randomization Analysis Metabolic syndrome Non-alcoholic Fatty Liver Disease - complications Non-alcoholic Fatty Liver Disease - genetics Nonalcoholic fatty liver disease Osteoporosis Osteoporosis - etiology Osteoporosis - genetics Risk Waist-Hip Ratio
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