Cytoplasmic and nuclear DROSHA in human villous trophoblasts

In villous trophoblasts, DROSHA is a key ribonuclease III enzyme that processes pri-microRNAs (pri-miRNAs) into pre-miRNAs at the placenta-specific, chromosome 19 miRNA cluster (C19MC) locus. However, little is known of its other functions. We performed formaldehyde crosslinking, immunoprecipitation...

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Veröffentlicht in:	Journal of reproductive immunology 2024-03, Vol.162, p.104189-104189, Article 104189
Hauptverfasser:	Noguchi, Syunya, Ohkura, Sadayuki, Negishi, Yasuyuki, Tozawa, Shohei, Takizawa, Takami, Morita, Rimpei, Takahashi, Hironori, Ohkuchi, Akihide, Takizawa, Toshihiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral defense DROSHA MicroRNA Sindbis virus Villous trophoblast VTRNA1–1
Online-Zugang:	Volltext
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