A New Rat Study Suggests There May Be a Biologic Explanation for Higher Fentanyl Mortality in Men Than in Women
Could it be possible that we should give some weight to the contribution of biological differences as contributors to the greater fentanyl mortality in males than in females? Most current explanations for a sex difference are based largely on psychosocial and other non-physiologic contributions. Our...
Gespeichert in:
| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2024-02, Vol.16 (2), p.e54354-e54354 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e54354 |
|---|---|
| container_issue | 2 |
| container_start_page | e54354 |
| container_title | Curēus (Palo Alto, CA) |
| container_volume | 16 |
| creator | Raffa, Robert B Pergolizzi, Jr, Joseph V Mathews, Jeanette Schatman, Michael E |
| description | Could it be possible that we should give some weight to the contribution of biological differences as contributors to the greater fentanyl mortality in males than in females? Most current explanations for a sex difference are based largely on psychosocial and other non-physiologic contributions. Our recent findings suggest a biological contribution. This could have broad implications for the interpretation and prevention of fentanyl overdose deaths. |
| doi_str_mv | 10.7759/cureus.54354 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2928587617</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2928587617</sourcerecordid><originalsourceid>FETCH-LOGICAL-c244t-832310ec88c4833e62c18f7cb68f8a918b75b7c2a873d91a825353f684b7d9f83</originalsourceid><addsrcrecordid>eNpd0c9LwzAUB_AgihP15lkCXjw4TfLa5vW4ib_AKfgDjyXN0tnRJTNp0f73Zk5FPOUdPnx5L19CDjg7lTLNz3TnTRdO0wTSZIPsCJ7hEDkmm3_mAdkPYc4Y40wKJtk2GQCC5AnkO8SN6J15pw-qpY9tN-3pYzebmdAG-vRqvKET1dOxoYqOa9e4Wa3pxceyUVa1tbO0cp5e17Mo6aWxrbJ9QyfOt6qp257Wlk6MjUHKruYXtzB2j2xVqglm__vdJc-XF0_n18Pb-6ub89HtUIskaYcIAjgzGlEnCGAyoTlWUpcZVqhyjqVMS6mFQgnTnCsUKaRQZZiUcppXCLvkeJ279O6tiwcVizpo08TVjetCIXKBKcqMy0iP_tG567yN20UFABHBSp2slfYuBG-qYunrhfJ9wVmx6qJYd1F8dRH54XdoVy7M9Bf__Dx8AqAcg3g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2933376137</pqid></control><display><type>article</type><title>A New Rat Study Suggests There May Be a Biologic Explanation for Higher Fentanyl Mortality in Men Than in Women</title><source>PubMed Central Open Access</source><source>PubMed Central</source><creator>Raffa, Robert B ; Pergolizzi, Jr, Joseph V ; Mathews, Jeanette ; Schatman, Michael E</creator><creatorcontrib>Raffa, Robert B ; Pergolizzi, Jr, Joseph V ; Mathews, Jeanette ; Schatman, Michael E</creatorcontrib><description>Could it be possible that we should give some weight to the contribution of biological differences as contributors to the greater fentanyl mortality in males than in females? Most current explanations for a sex difference are based largely on psychosocial and other non-physiologic contributions. Our recent findings suggest a biological contribution. This could have broad implications for the interpretation and prevention of fentanyl overdose deaths.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.54354</identifier><identifier>PMID: 38371439</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Females ; Fentanyl ; Males ; Mortality ; Non-binary gender ; Post traumatic stress disorder</subject><ispartof>Curēus (Palo Alto, CA), 2024-02, Vol.16 (2), p.e54354-e54354</ispartof><rights>Copyright © 2024, Raffa et al.</rights><rights>Copyright © 2024, Raffa et al. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c244t-832310ec88c4833e62c18f7cb68f8a918b75b7c2a873d91a825353f684b7d9f83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38371439$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Raffa, Robert B</creatorcontrib><creatorcontrib>Pergolizzi, Jr, Joseph V</creatorcontrib><creatorcontrib>Mathews, Jeanette</creatorcontrib><creatorcontrib>Schatman, Michael E</creatorcontrib><title>A New Rat Study Suggests There May Be a Biologic Explanation for Higher Fentanyl Mortality in Men Than in Women</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Could it be possible that we should give some weight to the contribution of biological differences as contributors to the greater fentanyl mortality in males than in females? Most current explanations for a sex difference are based largely on psychosocial and other non-physiologic contributions. Our recent findings suggest a biological contribution. This could have broad implications for the interpretation and prevention of fentanyl overdose deaths.</description><subject>Females</subject><subject>Fentanyl</subject><subject>Males</subject><subject>Mortality</subject><subject>Non-binary gender</subject><subject>Post traumatic stress disorder</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpd0c9LwzAUB_AgihP15lkCXjw4TfLa5vW4ib_AKfgDjyXN0tnRJTNp0f73Zk5FPOUdPnx5L19CDjg7lTLNz3TnTRdO0wTSZIPsCJ7hEDkmm3_mAdkPYc4Y40wKJtk2GQCC5AnkO8SN6J15pw-qpY9tN-3pYzebmdAG-vRqvKET1dOxoYqOa9e4Wa3pxceyUVa1tbO0cp5e17Mo6aWxrbJ9QyfOt6qp257Wlk6MjUHKruYXtzB2j2xVqglm__vdJc-XF0_n18Pb-6ub89HtUIskaYcIAjgzGlEnCGAyoTlWUpcZVqhyjqVMS6mFQgnTnCsUKaRQZZiUcppXCLvkeJ279O6tiwcVizpo08TVjetCIXKBKcqMy0iP_tG567yN20UFABHBSp2slfYuBG-qYunrhfJ9wVmx6qJYd1F8dRH54XdoVy7M9Bf__Dx8AqAcg3g</recordid><startdate>20240217</startdate><enddate>20240217</enddate><creator>Raffa, Robert B</creator><creator>Pergolizzi, Jr, Joseph V</creator><creator>Mathews, Jeanette</creator><creator>Schatman, Michael E</creator><general>Cureus Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>20240217</creationdate><title>A New Rat Study Suggests There May Be a Biologic Explanation for Higher Fentanyl Mortality in Men Than in Women</title><author>Raffa, Robert B ; Pergolizzi, Jr, Joseph V ; Mathews, Jeanette ; Schatman, Michael E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c244t-832310ec88c4833e62c18f7cb68f8a918b75b7c2a873d91a825353f684b7d9f83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Females</topic><topic>Fentanyl</topic><topic>Males</topic><topic>Mortality</topic><topic>Non-binary gender</topic><topic>Post traumatic stress disorder</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Raffa, Robert B</creatorcontrib><creatorcontrib>Pergolizzi, Jr, Joseph V</creatorcontrib><creatorcontrib>Mathews, Jeanette</creatorcontrib><creatorcontrib>Schatman, Michael E</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Raffa, Robert B</au><au>Pergolizzi, Jr, Joseph V</au><au>Mathews, Jeanette</au><au>Schatman, Michael E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A New Rat Study Suggests There May Be a Biologic Explanation for Higher Fentanyl Mortality in Men Than in Women</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2024-02-17</date><risdate>2024</risdate><volume>16</volume><issue>2</issue><spage>e54354</spage><epage>e54354</epage><pages>e54354-e54354</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Could it be possible that we should give some weight to the contribution of biological differences as contributors to the greater fentanyl mortality in males than in females? Most current explanations for a sex difference are based largely on psychosocial and other non-physiologic contributions. Our recent findings suggest a biological contribution. This could have broad implications for the interpretation and prevention of fentanyl overdose deaths.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>38371439</pmid><doi>10.7759/cureus.54354</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2168-8184 |
| ispartof | Curēus (Palo Alto, CA), 2024-02, Vol.16 (2), p.e54354-e54354 |
| issn | 2168-8184 2168-8184 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2928587617 |
| source | PubMed Central Open Access; PubMed Central |
| subjects | Females Fentanyl Males Mortality Non-binary gender Post traumatic stress disorder |
| title | A New Rat Study Suggests There May Be a Biologic Explanation for Higher Fentanyl Mortality in Men Than in Women |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-18T16%3A36%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20New%20Rat%20Study%20Suggests%20There%20May%20Be%20a%20Biologic%20Explanation%20for%20Higher%20Fentanyl%20Mortality%20in%20Men%20Than%20in%20Women&rft.jtitle=Cur%C4%93us%20(Palo%20Alto,%20CA)&rft.au=Raffa,%20Robert%20B&rft.date=2024-02-17&rft.volume=16&rft.issue=2&rft.spage=e54354&rft.epage=e54354&rft.pages=e54354-e54354&rft.issn=2168-8184&rft.eissn=2168-8184&rft_id=info:doi/10.7759/cureus.54354&rft_dat=%3Cproquest_cross%3E2928587617%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2933376137&rft_id=info:pmid/38371439&rfr_iscdi=true |