Whole-Genome Sequencing Analysis of Male Breast Cancer Unveils Novel Structural Events and Potential Therapeutic Targets

The molecular characterization of male breast cancer (MaBC) has received limited attention in research, mostly because of its low incidence rate, accounting for only 0.5% to 1% of all reported cases of breast cancer each year. Managing MaBC presents significant challenges, with most treatment protoc...

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Veröffentlicht in:	Modern pathology 2024-04, Vol.37 (4), p.100452-100452, Article 100452
Hauptverfasser:	Al Assaad, Majd, Michaud, Olivier, Semaan, Alissa, Sigouros, Michael, Tranquille, Marvel, Phan, Andy, Levine, Max F., Gundem, Gunes, Medina-Martínez, Juan S., Papaemmanuil, Elli, Manohar, Jyothi, Wilkes, David, Sboner, Andrea, Hoda, Syed A.F., Elemento, Olivier, Mosquera, Juan Miguel
Format:	Artikel
Sprache:	eng
Schlagworte:	breast cancer Breast Neoplasms - pathology Breast Neoplasms, Male - genetics Breast Neoplasms, Male - therapy DNA Helicases - genetics Female genomics Germ-Line Mutation homologous recombination deficiency Humans In Situ Hybridization, Fluorescence Male Mutation Nuclear Proteins - genetics Oncogenes structural variants Transcription Factors - genetics whole-genome sequencing
Online-Zugang:	Volltext
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