Beyond waste: understanding urine’s potential in precision medicine

Urine-derived stem cells (USCs) are a promising source of adult stem cells for cell therapy, drug testing for renal toxicity, and biomarker discovery in kidney disease.USCs can be non-invasively isolated from the donor’s own urine, making them a good candidate for precision medicine.Preclinical stud...

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Veröffentlicht in:	Trends in biotechnology (Regular ed.) 2024-08, Vol.42 (8), p.953-969
Hauptverfasser:	Yu, Pengfei, Bosholm, Carol Christine, Zhu, Hainan, Duan, Zhongping, Atala, Anthony, Zhang, Yuanyuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers Biomarkers - urine Biopsy Cartilage Cell therapy Cell- and Tissue-Based Therapy - methods Cloning Cryopreservation drug testing Humans Induced Pluripotent Stem Cells - cytology Kidney diseases Kidney Diseases - therapy Kidney Diseases - urine nephrotoxicity Pluripotency Precision medicine Precision Medicine - methods Regenerative medicine Stem Cells Telomerase Therapy tissue repair Toxic diseases Toxicity testing Urine Urine - chemistry Urogenital system
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