Screening for immune biomarkers associated with infection or protection against Ehrlichia ruminantium by RNA-sequencing analysis

Heartwater is one of the most economically important tick-borne fatal diseases of livestock. The disease is caused by the bacteria Ehrlichia ruminantium transmitted by Amblyomma ticks. Although there is evidence that interferon-gamma controls E. ruminantium growth and that cellular immune responses...

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Veröffentlicht in:	Microbial pathogenesis 2024-04, Vol.189, p.106588-106588, Article 106588
Hauptverfasser:	Pretorius, A., Nefefe, T., Thema, N., Liebenberg, J., Steyn, H., van Kleef, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers Challenge infection E. ruminantium Ehrlichia ruminantium - genetics Heartwater Heartwater Disease - diagnosis Heartwater Disease - prevention & control Leukocytes, Mononuclear Primary infection RNA RNA-sequencing Sheep Sheep PBMC Tick transmitted Ticks - microbiology Transcriptomics Vaccines, Synthetic
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