M6A modification regulates tumor suppressor DIRAS1 expression in cervical cancer cells

DIRAS family GTPase 1 (DIRAS1) has been reported as a potential tumor suppressor in other human cancer. However, its expression pattern and role in cervical cancer remain unknown. Knockdown of DIRAS1 significantly promoted the proliferation, growth, migration, and invasion of C33A and SiHa cells cul...

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Veröffentlicht in:	Cancer biology & therapy 2024-12, Vol.25 (1), p.2306674-2306674
Hauptverfasser:	Wang, Yu-Yan, Ye, Lian-Hua, Zhao, An-Qi, Gao, Wei-Ran, Dai, Ning, Yin, Yu, Zhang, Xin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine - analogs & derivatives Alpha-Ketoglutarate-Dependent Dioxygenase FTO Azacitidine - pharmacology Cervical cancer DIRAS1 epigenetic regulation Female GTP Phosphohydrolases Humans m6A Methyltransferases Research Paper RNA, Messenger - genetics Tumor Suppressor Proteins Uterine Cervical Neoplasms - genetics
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