Gamabufotalin inhibits colitis-associated colorectal cancer by suppressing transcription factor STAT3

Constitutive activation of STAT3 plays important role in the pathogenesis of colorectal cancer (CRC). Inhibition of STAT3 has been proposed as a reasonable strategy to suppress CRC. Gamabufotalin (Gam), an effective bioactive compound of ChanChu, has been used for cancer therapy due to its desirable...

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Veröffentlicht in:	European journal of pharmacology 2024-03, Vol.966, p.176372-176372, Article 176372
Hauptverfasser:	Jiang, Nian, Li, Sanhua, Meng, Lingjie, Zhang, Yao, Yu, Changyan, Xiao, Yi, Liu, Yun
Format:	Artikel
Sprache:	eng
Schlagworte:	Colitis-associated colorectal cancer Colorectal cancer Gamabufotalin STAT3
Online-Zugang:	Volltext
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