Evaluation of tendon and ligament microstructure and mechanical properties in a canine model of mucopolysaccharidosis I

Mucopolysaccharidosis (MPS) I is a lysosomal storage disorder characterized by deficient alpha‐l‐iduronidase activity, leading to abnormal accumulation of glycosaminoglycans (GAGs) in cells and tissues. Synovial joint disease is prevalent and significantly reduces patient quality of life. There is a...

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Veröffentlicht in:	Journal of orthopaedic research 2024-07, Vol.42 (7), p.1409-1419
Hauptverfasser:	Lau, Yian Khai, Iyer, Keerthana, Shetye, Snehal, Friday, Chet S., Dodge, George R., Hast, Michael W., Casal, Margret L., Gawri, Rahul, Smith, Lachlan J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Achilles Tendon - pathology Achilles Tendon - physiopathology Animals Anterior Cruciate Ligament - pathology Biomechanical Phenomena Disease Models, Animal dog Dogs Female hurler syndrome lysosomal storage disorder Male mucopolysaccharidoses Mucopolysaccharidosis I - pathology Mucopolysaccharidosis I - physiopathology synovial joint
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