PCSK9 dysregulates cholesterol homeostasis and triglyceride metabolism in olanzapine‐induced hepatic steatosis via both receptor‐dependent and receptor‐independent pathways

Schizophrenia, affecting approximately 1% of the global population, is often treated with olanzapine. Despite its efficacy, olanzapine's prolonged use has been associated with an increased risk of cardiovascular diseases and nonalcoholic fatty liver disease (NAFLD); however, the underlying mech...

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Veröffentlicht in:The FASEB journal 2024-02, Vol.38 (4), p.e23464-n/a
Hauptverfasser: Huang, Piaopiao, Ran, Juanli, Zhu, Wenqiang, Dai, Wen, Tang, Yaxin, Lian, Pingan, Huang, Xiansheng, Li, Rong
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Sprache:eng
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