A pH imbalance is linked to autophagic dysregulation of inner ear hair cells in Atp6v1ba-deficient zebrafish

V-ATPase is an ATP hydrolysis-driven proton pump involved in the acidification of intracellular organelles and systemic acid-base homeostasis through H+ secretion in the renal collecting ducts. V-ATPase dysfunction is associated with hereditary distal renal tubular acidosis (dRTA). ATP6V1B1 encodes...

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Veröffentlicht in:	Biochemical and biophysical research communications 2024-03, Vol.699, p.149551, Article 149551
Hauptverfasser:	Ikeuchi, Mayo, Inoue, Masanori, Miyahara, Hiroaki, Sebastian, Wulan Apridita, Miyazaki, Shuya, Takeno, Takashi, Kiyota, Kyoko, Yano, Shinji, Shiraishi, Hiroshi, Shimizu, Nobuyuki, Hanada, Reiko, Yoshimura, Akihiko, Ihara, Kenji, Hanada, Toshikatsu
Format:	Artikel
Sprache:	eng
Schlagworte:	ATP6V1B1 Atp6v1ba dRTA Hearing loss V-ATPase Zebrafish
Online-Zugang:	Volltext
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