Acceptability of a Randomized Trial of Anti-depressant Medication or Interpersonal Therapy for Treatment of Perinatal Depression in Women with HIV
Postpartum depression (PPD) affects nearly 20% of postpartum women in Sub-Saharan Africa (SSA), where HIV prevalence is high. Depression is associated with worse HIV outcomes in non-pregnant adults and mental health disorders may worsen HIV outcomes for postpartum women and their infants. PPD is eff...
Gespeichert in:
| Veröffentlicht in: | AIDS and behavior 2024-04, Vol.28 (4), p.1123-1136 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1136 |
|---|---|
| container_issue | 4 |
| container_start_page | 1123 |
| container_title | AIDS and behavior |
| container_volume | 28 |
| creator | Bridget Spelke, M. Okumu, Eunice Perry, Nzi R. Blette, Bryan S. Paul, Ravi Schiller, Crystal E. Ncheka, J. M. Kasaro, Margaret P. Price, Joan T. Meltzer-Brody, Samantha Stringer, Jeffrey S. A. Stringer, Elizabeth M. |
| description | Postpartum depression (PPD) affects nearly 20% of postpartum women in Sub-Saharan Africa (SSA), where HIV prevalence is high. Depression is associated with worse HIV outcomes in non-pregnant adults and mental health disorders may worsen HIV outcomes for postpartum women and their infants. PPD is effectively treated with psychosocial or pharmacologic interventions; however, few studies have evaluated the acceptability of treatment modalities in SSA. We analyzed interviews with 23 postpartum women with HIV to assess the acceptability of two depression treatments provided in the context of a randomized trial. Most participants expressed acceptability of treatment randomization and study visit procedures. Participants shared perceptions of high treatment efficacy of their assigned intervention. They reported ongoing HIV and mental health stigma in their communities and emphasized the importance of social support from clinic staff. Our findings suggest a full-scale trial of PPD treatment will be acceptable among women with HIV in Zambia. |
| doi_str_mv | 10.1007/s10461-023-04264-0 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2926522272</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2926522272</sourcerecordid><originalsourceid>FETCH-LOGICAL-c370t-36a4893ce7a864e8b04b6f5af0d29b163b49efca9ef9edb2e3d90fd45242252c3</originalsourceid><addsrcrecordid>eNp9kc2KFDEYRQtRnB99ARcScOMmmv9Uls2oMw0jirS6DKmqr5wMVUmZpJH2MXxi09ao4MJNEvKde0M4TfOEkheUEP0yUyIUxYRxTARTApN7zSmVmmPOpLhfz8QQrKmSJ81ZzreEEKO0edic8JZL3mp92vzY9D0sxXV-8uWA4ogc-uDCEGf_HQa0S95Nx9tNKB4PsCTI2YWC3sLge1d8DCgmtA0F0gIpx1Dx3Q0ktxzQWCe7BK7MUBO15D0kH1ypyKu16Rj3AX2OlUDffLlBV9tPj5oHo5syPL7bz5uPb17vLq7w9bvL7cXmGvdck4K5cqI1vAftWiWg7Yjo1CjdSAZmOqp4JwyMvauLgaFjwAdDxkFIJhiTrOfnzfO1d0nx6x5ysbPPPUyTCxD32TLDlGSMaVbRZ_-gt3Gf6l-PlFTGSEZ1pdhK9SnmnGC0S_KzSwdLiT0as6sxW43ZX8YsqaGnd9X7bobhT-S3ogrwFch1FL5A-vv2f2p_Ar-Not0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2956995217</pqid></control><display><type>article</type><title>Acceptability of a Randomized Trial of Anti-depressant Medication or Interpersonal Therapy for Treatment of Perinatal Depression in Women with HIV</title><source>SpringerLink Journals</source><source>Sociological Abstracts</source><creator>Bridget Spelke, M. ; Okumu, Eunice ; Perry, Nzi R. ; Blette, Bryan S. ; Paul, Ravi ; Schiller, Crystal E. ; Ncheka, J. M. ; Kasaro, Margaret P. ; Price, Joan T. ; Meltzer-Brody, Samantha ; Stringer, Jeffrey S. A. ; Stringer, Elizabeth M.</creator><creatorcontrib>Bridget Spelke, M. ; Okumu, Eunice ; Perry, Nzi R. ; Blette, Bryan S. ; Paul, Ravi ; Schiller, Crystal E. ; Ncheka, J. M. ; Kasaro, Margaret P. ; Price, Joan T. ; Meltzer-Brody, Samantha ; Stringer, Jeffrey S. A. ; Stringer, Elizabeth M.</creatorcontrib><description>Postpartum depression (PPD) affects nearly 20% of postpartum women in Sub-Saharan Africa (SSA), where HIV prevalence is high. Depression is associated with worse HIV outcomes in non-pregnant adults and mental health disorders may worsen HIV outcomes for postpartum women and their infants. PPD is effectively treated with psychosocial or pharmacologic interventions; however, few studies have evaluated the acceptability of treatment modalities in SSA. We analyzed interviews with 23 postpartum women with HIV to assess the acceptability of two depression treatments provided in the context of a randomized trial. Most participants expressed acceptability of treatment randomization and study visit procedures. Participants shared perceptions of high treatment efficacy of their assigned intervention. They reported ongoing HIV and mental health stigma in their communities and emphasized the importance of social support from clinic staff. Our findings suggest a full-scale trial of PPD treatment will be acceptable among women with HIV in Zambia.</description><identifier>ISSN: 1090-7165</identifier><identifier>EISSN: 1573-3254</identifier><identifier>DOI: 10.1007/s10461-023-04264-0</identifier><identifier>PMID: 38353877</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Acceptability ; Acquired immune deficiency syndrome ; AIDS ; Antidepressants ; Anxiety ; Behavior ; Counseling ; Data collection ; Health Psychology ; HIV ; Human immunodeficiency virus ; Infants ; Infectious Diseases ; Informed consent ; Interviews ; Medicine ; Medicine & Public Health ; Mental depression ; Mental disorders ; Mental health ; Original Paper ; Postpartum ; Postpartum depression ; Pregnancy ; Prenatal depression ; Public Health ; Randomization ; Social interactions ; Social support ; Stigma ; Treatment methods ; Women ; Womens health</subject><ispartof>AIDS and behavior, 2024-04, Vol.28 (4), p.1123-1136</ispartof><rights>The Author(s) 2024</rights><rights>2024. The Author(s).</rights><rights>The Author(s) 2024. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c370t-36a4893ce7a864e8b04b6f5af0d29b163b49efca9ef9edb2e3d90fd45242252c3</cites><orcidid>0000-0002-5950-8197</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10461-023-04264-0$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10461-023-04264-0$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,27901,27902,33751,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38353877$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bridget Spelke, M.</creatorcontrib><creatorcontrib>Okumu, Eunice</creatorcontrib><creatorcontrib>Perry, Nzi R.</creatorcontrib><creatorcontrib>Blette, Bryan S.</creatorcontrib><creatorcontrib>Paul, Ravi</creatorcontrib><creatorcontrib>Schiller, Crystal E.</creatorcontrib><creatorcontrib>Ncheka, J. M.</creatorcontrib><creatorcontrib>Kasaro, Margaret P.</creatorcontrib><creatorcontrib>Price, Joan T.</creatorcontrib><creatorcontrib>Meltzer-Brody, Samantha</creatorcontrib><creatorcontrib>Stringer, Jeffrey S. A.</creatorcontrib><creatorcontrib>Stringer, Elizabeth M.</creatorcontrib><title>Acceptability of a Randomized Trial of Anti-depressant Medication or Interpersonal Therapy for Treatment of Perinatal Depression in Women with HIV</title><title>AIDS and behavior</title><addtitle>AIDS Behav</addtitle><addtitle>AIDS Behav</addtitle><description>Postpartum depression (PPD) affects nearly 20% of postpartum women in Sub-Saharan Africa (SSA), where HIV prevalence is high. Depression is associated with worse HIV outcomes in non-pregnant adults and mental health disorders may worsen HIV outcomes for postpartum women and their infants. PPD is effectively treated with psychosocial or pharmacologic interventions; however, few studies have evaluated the acceptability of treatment modalities in SSA. We analyzed interviews with 23 postpartum women with HIV to assess the acceptability of two depression treatments provided in the context of a randomized trial. Most participants expressed acceptability of treatment randomization and study visit procedures. Participants shared perceptions of high treatment efficacy of their assigned intervention. They reported ongoing HIV and mental health stigma in their communities and emphasized the importance of social support from clinic staff. Our findings suggest a full-scale trial of PPD treatment will be acceptable among women with HIV in Zambia.</description><subject>Acceptability</subject><subject>Acquired immune deficiency syndrome</subject><subject>AIDS</subject><subject>Antidepressants</subject><subject>Anxiety</subject><subject>Behavior</subject><subject>Counseling</subject><subject>Data collection</subject><subject>Health Psychology</subject><subject>HIV</subject><subject>Human immunodeficiency virus</subject><subject>Infants</subject><subject>Infectious Diseases</subject><subject>Informed consent</subject><subject>Interviews</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Mental depression</subject><subject>Mental disorders</subject><subject>Mental health</subject><subject>Original Paper</subject><subject>Postpartum</subject><subject>Postpartum depression</subject><subject>Pregnancy</subject><subject>Prenatal depression</subject><subject>Public Health</subject><subject>Randomization</subject><subject>Social interactions</subject><subject>Social support</subject><subject>Stigma</subject><subject>Treatment methods</subject><subject>Women</subject><subject>Womens health</subject><issn>1090-7165</issn><issn>1573-3254</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>BHHNA</sourceid><recordid>eNp9kc2KFDEYRQtRnB99ARcScOMmmv9Uls2oMw0jirS6DKmqr5wMVUmZpJH2MXxi09ao4MJNEvKde0M4TfOEkheUEP0yUyIUxYRxTARTApN7zSmVmmPOpLhfz8QQrKmSJ81ZzreEEKO0edic8JZL3mp92vzY9D0sxXV-8uWA4ogc-uDCEGf_HQa0S95Nx9tNKB4PsCTI2YWC3sLge1d8DCgmtA0F0gIpx1Dx3Q0ktxzQWCe7BK7MUBO15D0kH1ypyKu16Rj3AX2OlUDffLlBV9tPj5oHo5syPL7bz5uPb17vLq7w9bvL7cXmGvdck4K5cqI1vAftWiWg7Yjo1CjdSAZmOqp4JwyMvauLgaFjwAdDxkFIJhiTrOfnzfO1d0nx6x5ysbPPPUyTCxD32TLDlGSMaVbRZ_-gt3Gf6l-PlFTGSEZ1pdhK9SnmnGC0S_KzSwdLiT0as6sxW43ZX8YsqaGnd9X7bobhT-S3ogrwFch1FL5A-vv2f2p_Ar-Not0</recordid><startdate>20240401</startdate><enddate>20240401</enddate><creator>Bridget Spelke, M.</creator><creator>Okumu, Eunice</creator><creator>Perry, Nzi R.</creator><creator>Blette, Bryan S.</creator><creator>Paul, Ravi</creator><creator>Schiller, Crystal E.</creator><creator>Ncheka, J. M.</creator><creator>Kasaro, Margaret P.</creator><creator>Price, Joan T.</creator><creator>Meltzer-Brody, Samantha</creator><creator>Stringer, Jeffrey S. A.</creator><creator>Stringer, Elizabeth M.</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T2</scope><scope>7U3</scope><scope>7U9</scope><scope>BHHNA</scope><scope>C1K</scope><scope>H94</scope><scope>K7.</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-5950-8197</orcidid></search><sort><creationdate>20240401</creationdate><title>Acceptability of a Randomized Trial of Anti-depressant Medication or Interpersonal Therapy for Treatment of Perinatal Depression in Women with HIV</title><author>Bridget Spelke, M. ; Okumu, Eunice ; Perry, Nzi R. ; Blette, Bryan S. ; Paul, Ravi ; Schiller, Crystal E. ; Ncheka, J. M. ; Kasaro, Margaret P. ; Price, Joan T. ; Meltzer-Brody, Samantha ; Stringer, Jeffrey S. A. ; Stringer, Elizabeth M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c370t-36a4893ce7a864e8b04b6f5af0d29b163b49efca9ef9edb2e3d90fd45242252c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Acceptability</topic><topic>Acquired immune deficiency syndrome</topic><topic>AIDS</topic><topic>Antidepressants</topic><topic>Anxiety</topic><topic>Behavior</topic><topic>Counseling</topic><topic>Data collection</topic><topic>Health Psychology</topic><topic>HIV</topic><topic>Human immunodeficiency virus</topic><topic>Infants</topic><topic>Infectious Diseases</topic><topic>Informed consent</topic><topic>Interviews</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Mental depression</topic><topic>Mental disorders</topic><topic>Mental health</topic><topic>Original Paper</topic><topic>Postpartum</topic><topic>Postpartum depression</topic><topic>Pregnancy</topic><topic>Prenatal depression</topic><topic>Public Health</topic><topic>Randomization</topic><topic>Social interactions</topic><topic>Social support</topic><topic>Stigma</topic><topic>Treatment methods</topic><topic>Women</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bridget Spelke, M.</creatorcontrib><creatorcontrib>Okumu, Eunice</creatorcontrib><creatorcontrib>Perry, Nzi R.</creatorcontrib><creatorcontrib>Blette, Bryan S.</creatorcontrib><creatorcontrib>Paul, Ravi</creatorcontrib><creatorcontrib>Schiller, Crystal E.</creatorcontrib><creatorcontrib>Ncheka, J. M.</creatorcontrib><creatorcontrib>Kasaro, Margaret P.</creatorcontrib><creatorcontrib>Price, Joan T.</creatorcontrib><creatorcontrib>Meltzer-Brody, Samantha</creatorcontrib><creatorcontrib>Stringer, Jeffrey S. A.</creatorcontrib><creatorcontrib>Stringer, Elizabeth M.</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Social Services Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Sociological Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Criminal Justice (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>AIDS and behavior</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bridget Spelke, M.</au><au>Okumu, Eunice</au><au>Perry, Nzi R.</au><au>Blette, Bryan S.</au><au>Paul, Ravi</au><au>Schiller, Crystal E.</au><au>Ncheka, J. M.</au><au>Kasaro, Margaret P.</au><au>Price, Joan T.</au><au>Meltzer-Brody, Samantha</au><au>Stringer, Jeffrey S. A.</au><au>Stringer, Elizabeth M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Acceptability of a Randomized Trial of Anti-depressant Medication or Interpersonal Therapy for Treatment of Perinatal Depression in Women with HIV</atitle><jtitle>AIDS and behavior</jtitle><stitle>AIDS Behav</stitle><addtitle>AIDS Behav</addtitle><date>2024-04-01</date><risdate>2024</risdate><volume>28</volume><issue>4</issue><spage>1123</spage><epage>1136</epage><pages>1123-1136</pages><issn>1090-7165</issn><eissn>1573-3254</eissn><abstract>Postpartum depression (PPD) affects nearly 20% of postpartum women in Sub-Saharan Africa (SSA), where HIV prevalence is high. Depression is associated with worse HIV outcomes in non-pregnant adults and mental health disorders may worsen HIV outcomes for postpartum women and their infants. PPD is effectively treated with psychosocial or pharmacologic interventions; however, few studies have evaluated the acceptability of treatment modalities in SSA. We analyzed interviews with 23 postpartum women with HIV to assess the acceptability of two depression treatments provided in the context of a randomized trial. Most participants expressed acceptability of treatment randomization and study visit procedures. Participants shared perceptions of high treatment efficacy of their assigned intervention. They reported ongoing HIV and mental health stigma in their communities and emphasized the importance of social support from clinic staff. Our findings suggest a full-scale trial of PPD treatment will be acceptable among women with HIV in Zambia.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>38353877</pmid><doi>10.1007/s10461-023-04264-0</doi><tpages>14</tpages><orcidid>https://orcid.org/0000-0002-5950-8197</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1090-7165 |
| ispartof | AIDS and behavior, 2024-04, Vol.28 (4), p.1123-1136 |
| issn | 1090-7165 1573-3254 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2926522272 |
| source | SpringerLink Journals; Sociological Abstracts |
| subjects | Acceptability Acquired immune deficiency syndrome AIDS Antidepressants Anxiety Behavior Counseling Data collection Health Psychology HIV Human immunodeficiency virus Infants Infectious Diseases Informed consent Interviews Medicine Medicine & Public Health Mental depression Mental disorders Mental health Original Paper Postpartum Postpartum depression Pregnancy Prenatal depression Public Health Randomization Social interactions Social support Stigma Treatment methods Women Womens health |
| title | Acceptability of a Randomized Trial of Anti-depressant Medication or Interpersonal Therapy for Treatment of Perinatal Depression in Women with HIV |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-08T01%3A05%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Acceptability%20of%20a%20Randomized%20Trial%20of%20Anti-depressant%20Medication%20or%20Interpersonal%20Therapy%20for%20Treatment%20of%20Perinatal%20Depression%20in%20Women%20with%20HIV&rft.jtitle=AIDS%20and%20behavior&rft.au=Bridget%20Spelke,%20M.&rft.date=2024-04-01&rft.volume=28&rft.issue=4&rft.spage=1123&rft.epage=1136&rft.pages=1123-1136&rft.issn=1090-7165&rft.eissn=1573-3254&rft_id=info:doi/10.1007/s10461-023-04264-0&rft_dat=%3Cproquest_cross%3E2926522272%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2956995217&rft_id=info:pmid/38353877&rfr_iscdi=true |