Enhancing CAR Macrophage Efferocytosis Via Surface Engineered Lipid Nanoparticles Targeting LXR Signaling

The removal of dying cells, or efferocytosis, is an indispensable part of resolving inflammation. However, the inflammatory microenvironment of the atherosclerotic plaque frequently affects the biology of both apoptotic cells and resident phagocytes, rendering efferocytosis dysfunctional. To overcom...

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Veröffentlicht in:	Advanced materials (Weinheim) 2024-05, Vol.36 (19), p.e2308377
Hauptverfasser:	Chuang, Skylar T, Stein, Joshua B, Nevins, Sarah, Kilic Bektas, Cemile, Choi, Hye Kyu, Ko, Wan-Kyu, Jang, Hyunjun, Ha, Jihun, Lee, Ki-Bum
Format:	Artikel
Sprache:	eng
Schlagworte:	Atherosclerosis Efflux In vivo methods and tests Lipids Macrophages Nanoparticles Phagocytosis Receptors
Online-Zugang:	Volltext
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