Platycodin D induces apoptosis via regulating MAPK pathway and promotes autophagy in colon cancer cell

Platycodin D (PD) is the main component of triterpene saponins found in Platycodi radix. In this study, we observed a decrease in cell viability, an increase in apoptotic bodies, and an increase in the rate of apoptosis. Also, we observed an increase in cleaved PARP and Bax, a decrease in Bcl-2, and...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2024-03, Vol.172, p.116216-116216, Article 116216
Hauptverfasser:	Han, So-Hee, Lee, Jae-Han, Woo, Joong-Seok, Jung, Gi-Hwan, Jung, Soo-Hyun, Han, Eun-Ji, Park, Young-Seok, Kim, Byeong-Soo, Kim, Sang-Ki, Park, Byung-Kwon, Jung, Ji-Youn
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Autophagy Colon cancer MAPK pathway Platycodin D
Online-Zugang:	Volltext
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