De novo thrombotic microangiopathy after kidney transplantation in adults: Interplay between complement genetics and multiple endothelial injury

De novo thrombotic microangiopathy (dnTMA), after renal transplantation may significantly alter graft outcomes. However, its pathogenesis and the role of complement alternative pathway dysregulation remain elusive. We studied all consecutive adult patients with a kidney allograft biopsy performed be...

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Veröffentlicht in:	American journal of transplantation 2024-07, Vol.24 (7), p.1205-1217
Hauptverfasser:	Dessaix, Kathleen, Bontoux, Christophe, Aubert, Olivier, Grünenwald, Anne, Sberro Soussan, Rebecca, Zuber, Julien, Duong Van Huyen, Jean-Paul, Anglicheau, Dany, Legendre, Christophe, Fremeaux Bacchi, Veronique, Rabant, Marion
Format:	Artikel
Sprache:	eng
Schlagworte:	biopsy complement alternative pathway de novo thrombotic microangiopathy kidney transplantation
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