Collagen Mineralization Decreases NK Cell‐Mediated Cytotoxicity of Breast Cancer Cells via Increased Glycocalyx Thickness

Skeletal metastasis is common in patients with advanced breast cancer and often caused by immune evasion of disseminated tumor cells (DTCs). In the skeleton, tumor cells not only disseminate to the bone marrow but also to osteogenic niches in which they interact with newly mineralizing bone extracel...

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Veröffentlicht in:	Advanced materials (Weinheim) 2024-10, Vol.36 (43), p.e2311505-n/a
Hauptverfasser:	Park, Sangwoo, Choi, Siyoung, Shimpi, Adrian A., Estroff, Lara A., Fischbach, Claudia, Paszek, Matthew J.
Format:	Artikel
Sprache:	eng
Schlagworte:	bone extracellular matrix Bone marrow Breast cancer Collagen collagen mineralization Flow cytometry glycocalyx Immune evasion Immune system Lipids Mineralization Optical properties Thickness Tumors
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