Differential effects of the lipidic and ionic microenvironment on NPP1's phosphohydrolase and phosphodiesterase activities

Ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) is an enzyme present in matrix vesicles (MV). NPP1 participates on the regulation of bone formation by producing pyrophosphate (PPi) from adenosine triphosphate (ATP). Here, we have used liposomes bearing dipalmitoylphosphatidylcholine (DPPC...

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Veröffentlicht in:	Biochimica et biophysica acta. Biomembranes 2024-04, Vol.1866 (4), p.184292, Article 184292
Hauptverfasser:	Andrilli, Luiz H.S., Sebinelli, Heitor G., Cominal, Juçara G., Bolean, Maytê, Hayann, Larwsk, Millán, José Luís, Ramos, Ana P., Ciancaglini, Pietro
Format:	Artikel
Sprache:	eng
Schlagworte:	AFM ATR-FTIR Biomineralization Liposomes NPP1 RAMAN
Online-Zugang:	Volltext
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