Up-regulation of RAN by MYBL2 maintains osteosarcoma cancer stem-like cells population during heterogeneous tumor generation

Intratumor heterogeneity is one of the major features of cancers, leading to aggressive disease and treatment failure. Cancer stem-like cells (CSCs) are believed to give rise to the heterogeneous cell types within tumors. Hence, understanding the regulatory mechanism underlying the recurrence proces...

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Veröffentlicht in:	Cancer letters 2024-04, Vol.586, p.216708-216708, Article 216708
Hauptverfasser:	Gao, Weijie, Zhou, Jing, Huang, Jintao, Zhang, Zhiguang, Chen, Wanqi, Zhang, Ruhua, Kang, Tiebang, Liao, Dan, Zhong, Li
Format:	Artikel
Sprache:	eng
Schlagworte:	Intratumor heterogeneity MYBL2 Osteosarcoma cancer stem-like cell RAN Single-cell transcriptomic
Online-Zugang:	Volltext
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