Vitamin C Inhibits Lipopolysaccharide-Induced Hyperinflammatory State of Chronic Myeloid Leukemia Cells through Purinergic Signaling and Autophagy

: Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the overproduction of white blood cells, leading to symptoms such as fatigue, infections, and other complications. CML patients must take measures to prevent infections to mitigate the exacerbation of cancer cell prol...

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Veröffentlicht in:	Nutrients 2024-01, Vol.16 (3), p.383
Hauptverfasser:	Pires, Daniela A, Brandão-Rangel, Maysa A R, Silva-Reis, Anamei, Olímpio, Fabiana R S, Aimbire, Flavio, Oliveira, Carlos R, Mateus-Silva, José R, Zamarioli, Lucas S, Bachi, André L L, Bella, Yanesko F, Santos, Juliana M B, Bincoletto, Claudia, Lancha, Jr, Antonio Herbert, Vieira, Rodolfo P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphate Adenosine Triphosphate - pharmacology Ascorbic Acid - pharmacology Autophagy B cells Bacterial infections Biological products industry Cancer therapies Cell culture Cytokines Cytotoxicity Drug resistance Humans Infections Interleukins Kinases Leukemia Leukemia, Myelogenous, Chronic, BCR-ABL Positive Lipopolysaccharides - pharmacology Receptors, Purinergic P2X7 Tumor necrosis factor Tumor necrosis factor-TNF Vitamin C
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