Circ-FOXO3 inhibits triple-negative breast cancer growth and metastasis via regulating WHSC1-H3K36me2-Zeb2 axis

Circular RNAs (circRNAs), a subclass of non-coding RNAs characterized by covalently closed continuous loops, play a key role in tumorigenesis and aggressiveness. However, the potential molecular mechanism of circRNAs in triple-negative breast cancer (TNBC) remains largely unknown. Exploring their ro...

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Veröffentlicht in:	Cellular signalling 2024-05, Vol.117, p.111079-111079, Article 111079
Hauptverfasser:	Chen, Danyang, Zeng, Shanshan, Qiu, Huisi, Yang, Mingqiang, Lin, Xin, Lv, Xinwu, Li, Pan, Weng, Shaojuan, Kou, Siyue, Luo, Kai, Liu, Zongcai, Yi, Yanmei, Liu, Hao
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line, Tumor Cell Proliferation - genetics circ-FOXO3 Forkhead Box Protein O3 - genetics Forkhead Box Protein O3 - metabolism Gene Expression Regulation, Neoplastic H3K36me2 modification Humans MicroRNAs - metabolism RNA, Circular - genetics Triple Negative Breast Neoplasms - metabolism Triple-negative breast cancer Tumor suppressor WHSC1
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