Veterinarians exposed to inhaled anesthetic present chromosome damage, apoptosis and cell cycle changes

This cross‐sectional study evaluated, for the first time, DNA damage, viability, and cell death of lymphocytes and cell cycle phases of mononuclear and polymorphonuclear cells in veterinarians exposed to the volatile anesthetic isoflurane. Veterinarians who were occupationally exposed to isoflurane...

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Veröffentlicht in:	Environmental and molecular mutagenesis 2024-01, Vol.65 (1-2), p.96-102
Hauptverfasser:	Braz, Mariana G., Figueiredo, Drielle B. S., Golim, Marjorie A., Grassi, Tony F., da Costa, Bruno R. B., De Martinis, Bruno S., Braz, Leandro G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia Anesthetics Apoptosis Blood cells Cell Cycle cell cycle phases Cell death Cell proliferation Cell viability Chromosomes Cross-Sectional Studies Cytotoxicity Damage assessment Deoxyribonucleic acid DNA DNA Damage DNA repair Environmental health Environmental monitoring Exposure Flow cytometry Gas chromatography Headspace Health risk assessment Histone H2A Humans Intervention Isoflurane Leukocytes (polymorphonuclear) Lymphocytes Mass spectrometry Mass spectroscopy micronucleus Micronucleus Tests - methods Occupational exposure Occupational Exposure - adverse effects Occupational Exposure - analysis Occupational hazards Occupational health Peripheral blood Veterinarians Veterinary surgeons volatile anesthetic Workplace diversity
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