Investigating the Cytosolic Delivery of Proteins by Lipid Nanoparticles Using the Chloroalkane Penetration Assay

Protein therapeutics are an expanding area for research and drug development, and lipid nanoparticles (LNPs) are the most prominent nonviral vehicles for protein delivery. The most common methods for assessing protein delivery by LNPs include assays that measure the total amount of protein taken up...

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Veröffentlicht in:Biochemistry (Easton) 2024-02, Vol.63 (4), p.512-522
Hauptverfasser: Wang, Jing, Zhang, Shiying, Li, Yamin, Xu, Qiaobing, Kritzer, Joshua A.
Format: Artikel
Sprache:eng
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