Host Subcellular Organelles: Targets of Viral Manipulation
Viruses have evolved sophisticated mechanisms to manipulate host cell processes and utilize intracellular organelles to facilitate their replication. These complex interactions between viruses and cellular organelles allow them to hijack the cellular machinery and impair homeostasis. Moreover, viral...
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| Veröffentlicht in: | International journal of molecular sciences 2024-02, Vol.25 (3), p.1638 |
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| container_issue | 3 |
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| container_title | International journal of molecular sciences |
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| creator | Song, Min Seok Lee, Dong-Kun Lee, Chung-Young Park, Sang-Cheol Yang, Jinsung |
| description | Viruses have evolved sophisticated mechanisms to manipulate host cell processes and utilize intracellular organelles to facilitate their replication. These complex interactions between viruses and cellular organelles allow them to hijack the cellular machinery and impair homeostasis. Moreover, viral infection alters the cell membrane's structure and composition and induces vesicle formation to facilitate intracellular trafficking of viral components. However, the research focus has predominantly been on the immune response elicited by viruses, often overlooking the significant alterations that viruses induce in cellular organelles. Gaining a deeper understanding of these virus-induced cellular changes is crucial for elucidating the full life cycle of viruses and developing potent antiviral therapies. Exploring virus-induced cellular changes could substantially improve our understanding of viral infection mechanisms. |
| doi_str_mv | 10.3390/ijms25031638 |
| format | Article |
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| source | MDPI - Multidisciplinary Digital Publishing Institute; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Antiviral agents Cells Chikungunya virus Cholesterol Cytokines Extracellular matrix Health aspects HIV Human immunodeficiency virus Hyaluronic acid Immune response Infection Infections Inflammation Influenza Lipids Pathogenesis Proteins Respiratory syncytial virus Rheumatoid arthritis Severe acute respiratory syndrome coronavirus 2 Viral infections Viruses |
| title | Host Subcellular Organelles: Targets of Viral Manipulation |
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