Kisspeptin-10 Improves Testicular Redox Status but Does Not Alter the Unfolded Protein Response (UPR) That Is Downregulated by Hypothyroidism in a Rat Model

Hypothyroidism compromises the testicular redox status and is associated with reduced sperm quality and infertility in men. In this regard, studies have demonstrated the antioxidant potential of kisspeptin in reproductive and metabolic diseases. In this study, we evaluate the effects of kisspeptin-1...

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Veröffentlicht in:	International journal of molecular sciences 2024-02, Vol.25 (3), p.1514
Hauptverfasser:	Santos, Luciano Cardoso, Dos Anjos Cordeiro, Jeane Martinha, Cunha, Maria Clara da Silva Galrão, Santos, Bianca Reis, Oliveira, Luciana Santos de, da Silva, Adriana Lopes, Barbosa, Erikles Macêdo, Niella, Raquel Vieira, de Freitas, Gustavo José Cota, Santos, Daniel de Assis, Serakides, Rogéria, Ocarino, Natália de Melo, Borges, Stephanie Carvalho, de Lavor, Mário Sérgio Lima, Silva, Juneo Freitas
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Apoptosis Enzymes Gene expression Genes Hypothyroidism Kinases Males Medical research Medicine, Experimental Oxidation Oxidative stress Protein expression Proteins Sperm Testes Thyroid hormones Transcription factors
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