Methylation of GPRC5A promotes liver metastasis and docetaxel resistance through activating mTOR signaling pathway in triple negative breast cancer

This study aims to explore the function and mechanism of G Protein-coupled receptor class C group 5 member A (GPRC5A) in docetaxel-resistance and liver metastasis of breast cancer. Single-cell RNA transcriptomic analysis and bioinformatic analysis are used to screen relevant genes in breast cancer m...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Drug resistance updates 2024-03, Vol.73, p.101063-101063, Article 101063
Hauptverfasser:	Ou, Xueqi, Tan, Yeru, Xie, Jindong, Yuan, Jingping, Deng, Xinpei, Shao, Ruonan, Song, Cailu, Cao, Xi, Xie, Xiaoming, He, Rongfang, Li, Yuehua, Tang, Hailin
Format:	Artikel
Sprache:	eng
Schlagworte:	Docetaxel resistance Liver metastasis MTOR N6-methyladenosine modulation Triple negative breast cancer
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!