Involvement of GAT2/Slc6a13 in hypotaurine uptake at fetal-facing plasma membrane of syncytiotrophoblasts at mid-to-late gestation in rats and mice

Hypotaurine, a precursor to taurine, is known for its antioxidant properties and is prominently present in fetal plasma and the placenta. Our previous research revealed that ezrin-knockout mice experience fetal growth retardation, coinciding with reduced hypotaurine levels in fetal plasma. This stud...

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Veröffentlicht in:	Placenta (Eastbourne) 2024-03, Vol.147, p.59-67
Hauptverfasser:	Nishimura, Tomohiro, Araki, Hikari, Higuchi, Kei, Noguchi, Saki, Saito, Kei, Hara, Kanako, Yagishita, Haruya, Akashi, Risa, Obata, Sakiko, Tomi, Masatoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Membrane - metabolism Female GAT2 Hypotaurine Membrane Transport Proteins - metabolism Mice Mice, Knockout Placenta - metabolism Pregnancy Rats RNA, Messenger - metabolism Syncytiotrophoblast Tandem Mass Spectrometry Taurine - analogs & derivatives Taurine - metabolism Taurine - pharmacology Transporter Trophoblasts - metabolism
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