Horizontal transfer of miR-383 sensitise cells to cisplatin by targeting VEGFA-Akt signalling loop

Background Cellular resistance to cisplatin has been one of the major obstacles in the success of combination therapy for many types of cancers. Emerging evidences suggest that exosomes released by drug resistant tumour cells play significant role in conferring resistance to drug sensitive cells by...

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Veröffentlicht in:	Molecular biology reports 2024-12, Vol.51 (1), p.286-286, Article 286
Hauptverfasser:	Raji, Grace R., Poyyakkara, Aswini, Sruthi, T. V., Edatt, Lincy, Haritha, K., Shankar, S. Sharath, Kumar, V. B. Sameer
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT protein Animal Anatomy Animal Biochemistry Apoptosis Biomedical and Life Sciences Cisplatin Cisplatin - pharmacology Drug resistance Ectopic expression Exosomes HeLa Cells Histology Horizontal cells Horizontal transfer Humans Life Sciences MicroRNAs MicroRNAs - genetics miRNA Morphology Original Article Proto-Oncogene Proteins c-akt - genetics Signal transduction Vascular endothelial growth factor Vascular Endothelial Growth Factor A - genetics
Online-Zugang:	Volltext
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