The Therapeutic Potential in Cancer of Terpyridine‐Based Metal Complexes Featuring Group 11 Elements

Terpyridine‐based complexes with group 11 metals emerge as potent metallodrugs in cancer therapy. This comprehensive review focuses on the current landscape of anticancer examples, particularly highlighting the mechanisms of action. While Cu(II) complexes, featuring diverse ancillary ligands, domina...

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Veröffentlicht in:	ChemMedChem 2024-05, Vol.19 (10), p.e202300645-n/a
Hauptverfasser:	Gil‐Moles, María, Concepción Gimeno, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - chemical synthesis Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Apoptosis Apoptosis - drug effects Biological activity Cancer Cancer therapies Cell Proliferation - drug effects Coordination Complexes - chemical synthesis Coordination Complexes - chemistry Coordination Complexes - pharmacology Coordination compounds Copper Copper - chemistry Copper - pharmacology Copper compounds Cytotoxicity Deoxyribonucleic acid DNA DNA-binding Drug Screening Assays, Antitumor Gold Grooves Group 11 Heavy metals Humans Intercalating agents Ligands Metal complexes Molecular Structure Neoplasms - drug therapy Neoplasms - pathology Nuclease Pyridines - chemical synthesis Pyridines - chemistry Pyridines - pharmacology Silver Structure-Activity Relationship Terpyridine Tumor cell lines
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